Assessing the impact of delays in onset of mild cognitive impairment on the

 
   Lead Investigator:    Matthew Davis
   Institution      :    Medicus Economics
   E-Mail           :    matthew.davis@medicuseconomics.com
   Proposal ID      :    501


   Publications:


1  Davis M, O'Connell T, Johnson S, Cline S, Merikle E, Martenyi F, Simpson K
   Modeling the Benefits of Delayed Onset of Mild Cognitive Impairment due to Alzheimer's Disease in the United States
   2016   Abstract  SMDM 38th Annual North American Meeting , 

   ACCEPTED



2  Davis M, O'Connell T, Johnson S, Cline S, Merikle E, Martenyi F, Simpson KN
   Estimating Alzheimer's disease progression rates from normal cognition through mild cognitive impairment and stages of dementia
   2018   Journal Article  Curr Alzheimer Res ,PMC6156780

   PUBLISHED





   Proposal Description:
   This project aims to assess transition probabilities between normal cognition, mild cognitive impairment, and Alzheimer's disease states, as well as transitions from these states to institutionalization or death.  The likelihood of transitioning will be estimated controlling for select patient characteristics and risk factors.  The resulting transition matrix will be used in developing a model to evaluate the progression to later stages of disease, as well as rates of institutionalization and death.